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carbamazepine will decrease the level or impact of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.posaconazole will enhance the level or outcome of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.modafinil will lessen the level or influence of iobenguane I 131 by O